I agree that the correct answer is Penn State, but I disagree about the Pitt game. While Pitt went on to have a ho-hum year, at the time, that win was a huge splash nationally. Solich at Ohio was a big story, Wannstedt at Pitt was a story, and the way the game ended, plus being the only college game on that Friday night, made for a great national story.
Add into that the fact that Wannstedt was Steve Pederson's first choice for a coach to replace Solich, and you had an extra element to that game, and an extra irony in the Ohio win. The thing about the Pitt win, however, was that it was sort of a flukey win, depending on not one, but two pick-sixes from Byrum, on top of a TD returned for a touchdown by Pitt. The Penn State win was much more of a workmanlike game. Ohio just went into Penn State, and won the game. Yes, Ohio had one flukey TD, but even without it, Ohio was the clear winner.
To me one game marked a beginning, and a promise of more good things to come, while the other simply was a statement that Ohio is a real team that on any given Saturday might beat anyone.