The MAC has 21 games vs "P" conference teams this season:

Akron at Penn State
Iowa State at Akron
Ball State at Illinois
Bowling Green at Michigan State
Bowling Green at Northwestern
Buffalo at Minnesota
Central Michigan at Kansas
Central Michigan at Syracuse
Central Michigan at Boston College
Eastern Michigan at Rutgers
Eastern Michigan at Kentucky
Kent State at Clemson
Kent State at Louisville
Miami at Notre Dame
Boston College at NIU
NIU at Nebraska
Ohio at Purdue
Kansas at Ohio
Toledo at Miami (Fla.)
Western Michigan at USC
Western Michigan at Michigan State

I think the MAC has a good chance of winning eight: both Ohio games, CMU at Kansas and BC, Akron's home game vs ISU, BG at MSU, EMU at Rutgers, and NIU's home game vs BC. CMU might also beat Syracuse, Fiami has a chance vs ND and Toledo could beat MiamiF.

Probably so, I'd say lucky to win 5

I think the MAC will be slightly favored in 3:
Kansas @ Ohio
EMU @ Rutgers
Ohio @ Pudue

I think there will be two pick ems:
WMU @ Mich St
CMU @ Kansas

I see 5 games where the MAC team has a shot:
Iowa St @ Akron
BC @ NIU
Ball St @ Illinois
CMU @ Syracuse
EMU @ Kentucky

When it's all done, I think the MAC wins 4-5 games. I added a few games to his list (WMU @ Mich St, Ball St * Ill, EMU @ Ky), and subtracted a few (Miami @ ND, CMU @ Syracuse, BG @ Mich St).