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CMU essentially has a lock with Kansas at home, and might get a win at Kentucky. Toledo played MiamiF tough on the road last year and has a good chance for a win at home (even without Woodside). WMU and NIU should be favored in their home games. Ohio has a very good shot at a win, and I expect Fiami to give Minnesota a tough game.
The only game where the MAC will likely be favored is Kansas @CMU
I see three games which are tossups:
Buffalo @Rutgers
Ohio @Virginia
Syracuse @WMU
I see three more where the MAC has a reasonable chance for an upset:
Maryland @BG
Utah @NIU
CMU @Kentucky
Figuring 80% chance of CMU beating Kansas, 50% on the tossups, and .25% on the next three, it looks like the MAC will about 3 games versus the P5 again this year, which is about the same as the last few years.